More contagious does not mean more lethality

 The coronavirus epidemic has taken a very deadly shape. It has had a devastating effect on the world.

 In this context, the World Health Organization (WHO) has warned that the ongoing disaster is not a major pandemic, it could lead to more pandemics. 

The world needs to prepare for that. And the world must learn to live with the moving corona.

The WHO spoke of this warning at the last media briefing of the year on Corona on Monday. The news agency AFP and The Guardian reported this information.

At the briefing, WHO expert Professor David Heyman said that even after the vaccine will be introduced, the corona's destiny will to become a local disease.

"It's a warning," said Michael Ryan, head of WHO's emergency program in Corona.

Michael Ryan said the pandemic is very deadly. It has spread around the world very fast. 

It has affected every corner of this planet. But it is certainly not a major pandemic.

Michael Ryan warns that a bigger and more deadly pandemic than Corona could come in the future. And he thinks that the world should seriously prepare for this.

New strain

Corona-Panic has recently added a new name to the world - 'UK Strain'. Its scientific name is VUI-202012/01. 

The British government itself has warned that the coronavirus strain has a transmission rate of more than 70 per cent.

This type of coronavirus was first identified in September this year, according to a leading British news agency. 

Some countries like Italy and Australia have claimed that the strain has been detected in their countries as well. 

Many countries have cut ties with Britain out of fear. The RT-PCR test has been made mandatory as soon as a passenger from Britain lands at the country's airport.

There is only one reason for such fear - mutations in the virus. 

The reason for naming the new type of virus as 'VUI-202012/01' is 'VUI' meaning 'Virus Under Investigation'.

 That means the virus is under investigation. According to the European Center for Disease Prevention and Control, this is very different from the first identified Uhan strain. 

A total of 29 nucleotide substitution mutations have occurred. One of these mutations is 'N501Y'. 

This change occurs in the receptor-binding domain of the spike protein of the virus. 

This receptor binding domain of the spike protein is responsible for binding to the ACE 2 receptor in the human cell.

 The virus enters the human body in this way. The mutation increased that infecting ability.

But an increase in infectivity does not mean an increase in lethality. ‘Transmission’ means the spread of the virus from one person to another. 

‘Virulence’ is different. It means how much harmful it is. 

Being more contagious does not mean being more harmful. Ability to harm of a virus could be equal, even if it is more contagious.

 Not enough information is known about the virus at this time. As a result, there is no evidence that it is more harmful. 

It is not even possible to say that the spike of the virus has mutated in the ‘receptor binding domain’ of the protein, increasing its ability to bind to the ‘ACE 2 receptor’ in the human cell. 

It could also be that this mutation has created the ability for the virus to attach to any receptor in the human cell other than ACE2.

In this situation, the question arises again and again: the possible vaccines that have been developed, will they help to prevent this new type of coronavirus, or not? But the answer is not yet known.

 In this case, it is important to know whether this type of coronavirus is different from an antigen.

 In that case, the body's immune system will respond differently. The process of preventing the virus will be different in that case. 

However, the whole matter is now under investigation. That is why it has been said from the beginning - 'Virus Under Investigation'.

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