Confusion over AstroZeneca's vaccine

The world heard the good news about the coronavirus vaccine last week from AstraZeneca and Oxford Universities in the United Kingdom. That said, the vaccine has shown widespread effectiveness in the final stages of testing. 

The vaccine raised new hopes in the fight against the Corona epidemic. It was available at a lower price than the Corona Ticker of Moderna, Pfizer and their German partner Bio N Tech in the United States, as well as easy delivery. But now some negative news has started coming around this vaccine. This information has been informed in a report of BBC Online.

Several media outlets in the United Kingdom and the United States on Thursday questioned the information on the AstraZeneca ticker. Most questions are raised about the effectiveness of the tick.

AstraZeneca reported three types of results from their vaccine tests. They say the total effectiveness of the vaccine will be 80 percent. In this case, the minimum efficiency is 72 percent and the maximum efficiency is 90 percent.

 The reason for this result is that different types of doses were used incorrectly during the vaccine test. Some volunteers who took part in the immunization test were mistakenly given a half-strength dose of the vaccine as planned. But the test results showed that the wrong dose is good.

This means that some doses of the vaccine were made less potent than planned. The ingredients used to make the vaccine were also added less. That is why it has been possible to protect a person.

According to the BBC, the AstraZeneca vaccine is usually taken in two doses. One month after the first vaccination, another dose should be taken as a booster. Most volunteers received the usual two doses during the vaccination test. 

Some volunteers mistakenly give low energy doses. The researchers had earlier admitted the mistake to vaccine regulators. They agreed to continue the vaccination test, including more volunteers.

In the end, however, the error did not affect the safety of the tick.

Three thousand volunteers were given another half-dose four weeks after receiving one dose. In their case, the effectiveness of the vaccine is seen up to 90 percent. On the other hand, after giving two full doses of vaccine to 9,000 people, their effectiveness was found to be 72 percent.

AstraZeneca published the results of two tests. In addition, they claim that the average effectiveness of their vaccine against protection froms 80 percent. Many experts started raising questions about this result.

Professor David Salisbury, a Fellow and Vaccine Specialist at the World Health Organization, said the results of two different doses were being combined in two trials, which were not the results of either. That's why people can't catch it.

AstraZeneca says, however, that this is their primary information. This is not final information. This also applies to Pfizer and Moderna.

Vaccine manufacturers are required to publish the full results of their vaccine tests in a medical journal for review. Regulators are already being contacted to review the complete information to get urgent approval of the vaccine from the organizations.

The FDA, the U.S. vaccine regulator, says any vaccine for COVID must be proven to be at least 50 percent effective. AstraZeneca, of course, meets this condition. Their lowest vaccination rate is 72 percent.

Researchers at Oxford are currently working to show that low-dose vaccines are more effective.

Many experts, however, also praise the Oxford vaccine. Although the dose levels vary, vaccine research has progressed according to the actual plan.

“We can get a message here that we are going to get three potential COVID vaccines soon, which will help save lives,” said Peter Openshaw, an expert professor at Imperial College London. But we will have to wait to get the final and complete information and see how the regulators review it. The Oxford vaccine is less effective than the mRNA vaccine, but we will have to wait and see.

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